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Directions

About Directions

Getting to Center City Campus

Jefferson's main campus is minutes away from major roads and within walking distance of mass transportation services. Here are directions to our campus by car and public transportation.

By Car
From Betsy Ross Bridge and Points Northeast of Philadelphia
  • Take I-95 South to Exit 22 (Central Philadelphia/Independence Hall/Callowhill Street).
  • At the end of the ramp, turn right onto Callowhill Street.
  • Continue on Callowhill Street to 8th Street.
  • Turn left onto 8th Street. Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right.
  • Follow 11th Street to Jefferson's campus.

From Delaware and Points South of Philadelphia
  • Take Rt. I-95 North to Exit 22 (Central Phila./Independence Hall/Callowhill Street) - a left-lane exit.
  • Stay in right lane and exit onto Callowhill Street.
  • Once on Callowhill Street, stay in middle lane and continue to 8th Street.
  • Turn left onto 8th Street. Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right.
  • Follow 11th Street to Jefferson's campus.

From Main Line
  • Take Route 476 North to exit 16A (Route 76 East/Schuylkill Expressway) to Philadelphia.
  • Take Exit 344 (Central Phila./676 East) - a left-lane exit.
  • Take the Broad Street Exit - a right-lane exit.
  • Stay in left lane and follow signs for Vine Street.
  • Follow Vine Street to 10th Street and turn right onto 10th Street.
  • Follow 10th Street to Jefferson’s campus.

From New Jersey Turnpike
  • Take Exit 4 (73 West) off NJ Turnpike.
  • Follow 73 West to 38 West.
  • Continue on 38 West, following signs for the Ben Franklin Bridge. (38 West will turn into Admiral Wilson Boulevard.) Continue to bridge.
  • Take bridge and stay in left lane and turn left on 8th Street.
  • Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right.
  • Follow 11th Street to Jefferson's campus.

From New Jersey via Ben Franklin Bridge
  • Take bridge and stay in left lane and turn left on 8th Street.
  • Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right.
  • Follow 11th Street to Jefferson’s campus.

From New Jersey via Walt Whitman Bridge
  • Cross Walt Whitman Bridge. After the toll booth, take I-95 North to Exit 22 (Central Phila./Independence Hall/Callowhill Street) - left-lane exit.
  • At the end of the ramp, turn right onto Callowhill Street.
  • Once on Callowhill Street, stay in middle lane and continue to 8th Street.
  • Turn left onto 8th Street. Follow 8th Street to Spruce Street and turn right.
  • Follow Spruce Street to 11th Street and turn right.
  • Follow 11th Street to Jefferson's campus.

From Points North and West of Philadelphia (76 East)
  • Take PA Turnpike to Exit 326 (Valley Forge).
  • Take 76 East (Schuylkill Expressway) to Philadelphia.
  • Take Exit 344 (Central Philadelphia/676 East) - a left-lane exit.
  • Take the Broad Street Exit - a right-lane exit.
  • Get into left lane and follow signs for Vine Street.
  • Follow Vine Street to 10th Street and turn right onto 10th Street.
  • Follow 10th Street to Jefferson's campus.

From Route 309
  • Take Route 309 South to the end of the expressway.
  • Turn left onto Cheltenham Avenue to Route 611 (Broad Street).
  • Turn right onto Route 611 South (Broad Street).
  • Continue on Broad Street (approximately 6 miles) to Vine Street.
  • Turn left onto Vine Street (outside lane) and follow to 10th Street.
  • Turn right onto 10th Street.
  • Follow 10th Street to Jefferson's campus. 

From Route 476
  • Take Exit 20 and follow signs for Route 476. Take Route 476 to Exit 16A; then take Route 76 East (Schuylkill Expressway) to Philadelphia.
  • Take Exit 344 (Central Phila/676 East) - a left-lane exit.
  • Take the Broad Street Exit - a right-lane exit.
  • Get into left lane and follow signs for Vine Street.
  • Follow Vine Street to 10th Street and turn right onto 10th Street.
  • Follow 10th Street to Jefferson's campus. 

By Public Transit
From New Jersey
  • Take the PATCO High Speed Line to the 10th and Locust Station.
  • Follow signs to 10th Street; this is the corner of the Jefferson campus.

From Northeast Philadelphia
  • Take westbound Market-Frankford elevated to 11th and Market Streets.
  • Walk south on 11th Street one block to the Jefferson campus at 11th and Chestnut Streets.

From South Philadelphia
  • Take Broad Street subway to Broad and Locust Streets.
  • Walk east on Locust Street three blocks to the Jefferson campus at 11th and Locust Streets.

From Suburbs
  • Call SEPTA at 215-580-7800 to determine the regional rail line closest to your home.
  • Take the train to the Market East Station at 11th and Market Streets.

From West Philadelphia
  • Take the eastbound Market-Frankford elevated to 11th and Market Streets.
  • Walk south on 11th Street one block to the Jefferson campus at 11th and Chestnut Streets.