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The Daily Dose @Jefferson

January 13, 2011

Colonoscopy Reduces Risk of Colorectal Cancer 77 Percent, Study Finds

Dr. Prieto, Jorge

Dr. Jorge A. Prieto

Benjamin Franklin probably didn’t have colorectal cancer in mind when he said that an ounce of prevention is worth a pound of cure. But if you are at high risk due to your family history or other factors, or if you’ve turned 50 and are due for a colonoscopy, a new study highlights the importance of undergoing the cancer screening procedure.

Researchers in Germany undertook a large population-based cohort study to determine if colonoscopies available in community hospitals and outpatient centers – not just those by experts at academic medical centers – provide a high degree of protection.

The results were remarkable overall: having a colonoscopy was associated with a 77 percent lower risk of developing colorectal cancer. Even more impressive, researchers found that the risk of right-sided colon cancer (the most difficult to identify with a colonoscopy) was reduced by 56 percent.

“Strong risk reduction was observed for all cancer stages, in both women and men, and in all age groups," the researchers concluded. “And risk reduction increased over time, reaching 82 percent overall in the most recent period studied, 2006-2007.”

After reviewing the study published in the current issue of the Annals of Internal Medicine, Jefferson gastroenterologist Jorge A. Prieto, MD said that it confirmed the absolute necessity that people at high risk or for whom colonoscopy is age appropriate need to go have the procedure done.

“Ultimately, what we are looking for is that fewer people die of colon cancer,” Dr. Prieto said. And early detection through colonoscopies is critical, he added.

The American Cancer Society estimates that in 2010 more than 142,500 people in the U.S. were diagnosed with colorectal cancer. In addition, some 51,000 people died of the disease, including 4,370 in Pennsylvania, New Jersey and Delaware.

If you are (or have been) diagnosed with colorectal cancer, the Jefferson Colon and Rectal Cancer Center provides a multidisciplinary approach to study and treat colon and rectal cancer with a team of colorectal surgeons, medical oncologists, surgical pathologists, radiation oncologists, geneticists and radiologists.

Comments

  • Rob
    6/22/2011 11:53 AM

    Medical screening statistics like these are rather deceitful and misleading when you look at absolute risk factors.

    For example:
    Most studies show that the absolute lifetime risk of dying from colon cancer is between 2 and 6.9%, depending on hereditary risk factors. Let's say one is in the very highest risk factor: 6.9%. According to the study cited above, colonosocopy screening could possibly reduce that risk by 77%. Reducing 6.9 by 77% improves my odds from 6.9 out of 100 to 1.59 out of 100.. Or, another way of looking at..Without Colonoscopy Screening, I would have 93.1% chance living a full life without Colon Cancer. With Colonoscopy screening, I've improved my odds to 98.4%. The benefits of screening are not nearly so impressive when you look at absolute risk factors instead of relative risk factors. Also, the 78% is for cancer reduction, not mortality reduction which is probably closer to 30%..

    I'm not telling people past age 50 to NOT get colonoscopies, but let's be realistic about their actual benefits.



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