Ongoing Research
There are approximately 17,000 primary brain tumors diagnosed in the United States each year, 60 percent of which are gliomas. Minimizing neurological side effects in patients with high-grade gliomas from chemoradiation may result in improved patient survival, a new study from our radiation oncologists suggests.
It is generally considered that the only way to improve survival in malignant brain tumors is to more effectively attack the tumor. However, our research suggests that damage to surrounding normal tissue may also play a role in determining a patient's long-term outcome.
Other researchers from Jefferson have found that patients who received hypofractionated stereotactic radiotherapy for their recurrent brain cancers lived longer lives.
Not only does hypofractionated stereotactic radiotherapy provide longer survival, patients do not experience side effects commonly seen with use of chemotherapies and targeted therapies. These findings set a new bar for the treatment of recurrent gliomas.