Jefferson Hospital for Neuroscience Receives National Award From Department of Health and Human Services
(Published: 12-23-2008) The Department of Health and Human Services recently awarded Jefferson Hospital for Neuroscience (JHN)
the Medal of Honor for achieving a lifesaving organ donation conversion rate of 75 percent or greater for a sustained 12-month
period. The award was given during the fourth National Learning Congress held in Nashville, Tennessee in October.
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Alzheimer's Researchers Receive Award in Philadelphia
(Published 10-22-06) Thomas Jefferson University presents a cash prize to the pioneers of Alzheimer's research.
Dr. Sam Gandy is the Director of Thomas Jefferson University's Farber Institute for Neurosciences. He says the Lennox K Black
Prize is given to the men and women who lead the way in medical research.
Former U.S. Attorney General Janet Reno will also be at the symposium to talk about Parkinson's disease, which she's had for
more than a decade.
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Former U.S. Attorney General Janet Reno to Offer Personal View of Parkinson’s disease at Jefferson’s Lennox K. Black Symposium
(Published 10-20-06) Former U.S. Attorney General Janet Reno, who has been diagnosed with Parkinson’s disease, will discuss
her “personal perspective” on the neurological disease at a public session during the fourth Lennox K. Black International
Prize for Excellence in Medicine symposium. Ms. Reno’s talk will be held on the first day of the two-day symposium, whose
theme is the “Molecular Basis of Neurological Disease.”
Former U.S. Attorney General Janet Reno to Offer Personal View of Parkinson’s disease at Jefferson’s Lennox K. Black Symposium
(Published 10-11-06) Former U.S. Attorney General Janet Reno, who has been diagnosed with Parkinson’s disease, will discuss
her “personal perspective” on the neurological disease at a public session during the fourth Lennox K. Black International
Prize for Excellence in Medicine symposium. The event will be held at Thomas Jefferson University on Monday, October 23, at
5 p.m.
Obesity Tied to Higher Risk of Complications in Spinal Surgery, Jefferson Neurosurgeon Finds
(Published 10-9-06) While obesity is famously tied to increasing risks for heart disease and diabetes, now comes another reason
to lose weight: being obese may contribute to a greater likelihood of complications in delicate spine surgery.
Jefferson Orthopaedic Surgeons Leading International Study of Timing of Spinal Surgery
(Published 10-3-06) Surgeons at the Rothman Institute at Thomas Jefferson University Hospital are trying to answer a very
difficult and controversial question: Should surgeons operate immediately, within hours of a severe spinal injury, to try
to limit the damage to the spinal cord and surrounding tissues, as many surgeons believe? Or won't it make a difference in
how a patient ultimately fares, as others, citing their experiences, say?
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They've got your back - and heart, head, feet...
(Published 8-27-06, The Philadelphia Inquirer) Patient advocates navigate the health-care system, identify specialists, translate
doctorese, and negotiate insurance claims for patients who need guidance.
Bill Wynn was told by a doctor he had a brain tumor that had to be removed. With the advice of Betty Long, R.N., health advocate,
Wynn made an appointment with David Andrews, M.D., neurosurgeon at Thomas Jefferson University Hospital.
After some tests, Dr. Andrew explained that it might only be inflammation from an infection not a tumor at all.
"That's great," Long said, beaming. Her counsel had spared Wynn a risky surgery and, it appeared, he might not need any procedure
at all.
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A Grief Observed
(Published 8-25-06, Philadelphia City Paper) Saturday, April 8: My husband Mike was diagnosed with a benign brain tumor (craniopharyngioma)
in October 2005. His only symptom was a glare in his peripheral vision. If left untreated, these tumors halt all pituitary
functioning, cause blindness, neurological and personality changes.
The frankness of Danna Young's first blog entry might baffle anyone accustomed to snarky online rants about a band, movie
or political guffaw. But when Danna started "185 Craniopharyngiomas Walk Into a Bar" in April of this year, she had no way
of knowing how extensive the chronicle would become, or that she would end up sharing intimate details about her husband's
roller coaster illness with all the patience of a dedicated scientist and the healthy skepticism of a seasoned journalist.
"Craniopharyngioma is a less common disease that we treat," says David Andrews, professor of neurological surgery at Thomas
Jefferson University Hospital, and one of Mike's doctors.
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Minimally Invasive Spine Surgeon John Kevin Ratliff, M.D., Joins Jefferson’s Dept. of Neurological surgery
(Published 8-23-06) John Kevin Ratliff, M.D., a specialist in minimally invasive surgery (MIS) of the spine, has been named
assistant professor of neurological surgery and orthopaedic surgery at Jefferson Medical College of Thomas Jefferson University
in Philadelphia.
Multidisciplinary Brain Tumor Center Opens at Jefferson’s Kimmel Cancer Center(Published 7-28-06) Taking advantage of a 12-year history of providing the most innovative treatment for patients with brain
tumors, physicians in three departments of the Kimmel Cancer Center at Thomas Jefferson University and Thomas Jefferson University
Hospital have joined together to expand the service.
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Top Docs 2006
(Published 7-05-06) Among the 2006 "Top Docs" profiled in Philadelphia Magazine are Barry Rovner, M.D., geriatric psychiatrist
and director of the Alzheimer’s Center at the Farber Institute for Neuroscience, Thomas Jefferson University, and neurologist
Rodney Bell, M.D., director of the Acute Stroke Center at Thomas Jefferson University Hospital.
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Study targets protein seen as indicator of Alzheimer’s disease(Published 6-26-06, Associated Press) Brain deposits of a small protein known as amyloid beta long have been associated with
Alzheimer’s. Scientists are hoping that a new test enabling them to monitor the protein will help determine whether the body
begins producing too much of the protein or loses the ability to clear it away.
Six healthy volunteers were recently tested and it was determined that the protein is quickly produced and quickly cleared,
keeping it in balance with the central nervous system. While the researchers next turn to patients with Alzheimer’s, Sam Gandy,
M.D., Ph.D., Director of the Farber Institute for Neurosciences of Thomas Jefferson University says that the challenge is
to find clues to the developing disease before symptoms begin to appear. For now, Dr. Gandy says that this development “is
much more likely to be useful as a research tool than as a clinical diagnostic test.”
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Artificial light increases breast cancer risk(Published 6-20-06, The Daily Mail) Women who sleep with the light on or stay up late at night could be at a greater risk
of breast cancer, according to scientists. Researchers have long suggested that being exposed to too much light at night disrupts
crucial hormones and raises the chance of developing breast tumor.
If the link between tumor growth and light is confirmed by more studies, it could result in a change in working patterns.
Professor George Brainard, of the Thomas Jefferson University in Philadelphia, added: "Humans evolved on a planet without
electric light over thousands of thousands of generations. "The body is designed to be alert and awake during the daytime
hours and to sleep at night. "Now we have a 24-7 society that isn't in harmony with our biological design."
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Stroke Survivors and Supporters to Take on “Strides for Stroke” 5k Run/Walk in Honor of Jefferson Urologist(Published 5-2-06) Delaware Valley Stroke Council is sponsoring “Strides for Stroke,” a 5K run/walk. Money raised through
the event will support the council’s efforts to reduce the number of strokes through heightened public awareness, community
education and legislative and patient advocacy.
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Wrapping Radiation Around Tumors
(Published 5-8-06, ABC 7 Chicago) Walter J. Curran, M.D., professor and chair of Radiation Oncology at Jefferson Medical College
of Thomas Jefferson University and clinical director of the Kimmel Cancer Center at Jefferson, discusses Shaped Beam Surgery,
a new type of targeted radiation for hard-to-treat brain tumors.
“We have the ability to define a target, and give a dose to that target with relatively little dose to the surrounding structures.
Because this new technology is so precise, people can be treated with radiation a second time. The system not only treats
brain and spinal tumors; it is also being used to treat liver, lung, head and neck and prostate cancers,” said Dr. Curran.
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Tiny Coils New Way To Fix Burst Aneurysm(Published 5-1-06, NBC10) While most strokes -- or brain attacks -- happen when an artery to the brain gets blocked, 20 to
25 percent are due to bleeding when an abnormal blood vessel bursts.
Now, many people who survive a burst aneurysm can avoid having their skulls opened in a craniotomy because there is a unique,
safer way to fix the problem.
A few weeks ago Judy Goatley felt awful.
"I was just going back and forth like I had a few drinks too many or something," Goatley said.
Goatley burst an aneurysm -- just like 24-year-old Lauren Klein did one night in Harrisburg.
"I was getting into bed and I experienced a really sharp pain in my head and I said, 'I have to lie down. I have to lie down.'
And next thing I knew, I woke up in Thomas Jefferson University Hospital and I had had a brain aneurysm rupture," Goatley
said.
An aneurysm is a bubble on an artery that can burst and cause a subarachnoid hemorrhage -- otherwise known as a stroke.
"Once an aneurysm ruptures or bleeds, there is a 50 percent chance of dying or being disabled regardless of the treatment,"
said Dr. Robert Rosenwasser, chair of neurosurgeon at Thomas Jefferson University Hospital.
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Jefferson’s Acute Stroke Center Will Try to Block “Brain Attacks” With Free Stroke Risk Assessments(Published 4-21-06) The Acute Stroke Center at Thomas Jefferson University Hospital will provide free screenings and counseling
to identify men and women at risk for stroke on Tuesday, May 9, in the Women’s Resource Center at Jefferson Hospital’s Gibbon
Building S. 10th Street between Chestnut and Sansom streets, Philadelphia. The screenings will take place from 10 a.m. to
2 p.m.
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Eye cells that don't see, but regulate
(Published 4-16-2006, The Philadelphia Inquirer) As any good high school biology student can tell you, the human eye sees
light with special cells called rods and cones.
But when George C. Brainard Ph.D., director of the Light Research Program at Thomas Jefferson University, experimented with
shining various colors of light into people's eyes, something odd happened:
A specific shade of blue light was most effective at shutting down the body's production of melatonin - the "hormone of darkness"
that helps regulate sleep and the body's internal clock. Yet that shade of blue is not one of the colors best detected by
rods and cones.
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Locally Injected Steroids May Not Do Much Good for Chronic Headache Pain, Jefferson Researchers Find
(Published 4-11-06) Locally injected steroids apparently don’t enhance treatments for acute headache or migraine pain. A study
by neurologists at the Jefferson Headache Center at Thomas Jefferson University Hospital in Philadelphia did not show any
benefit to adding steroids to local anesthetics to treat daily headaches.
Live on the Web--Jefferson Surgeons Perform Leading Edge Minimally Invasive Surgery to Remove Pituitary Tumor
(Published 4-5-06) Breakthrough procedure allows doctors to remove brain tumors through nose and nasal sinuses Jefferson will
host a webcast featuring the newest approach for the removal of pituitary tumors – minimally invasive endoscopic pituitary
surgery – on Tuesday, May 23, 2006, at 4:30 pm. Viewers will also be able to ask questions online of the surgical team during
the surgery.
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Disease may be type of diabetes(Published 3-24-06, HealthDay) Giving more weight to the notion that Alzheimer’s may be a diabetes-like disease, researchers
say rats depleted of insulin in the brain went on to develop an Alzheimer’s-like illness.
By depleting insulin and its related proteins in the rodents’ brains, the researchers say, they have been able to replicate
the progression of Alzheimer's disease, including such characteristics as amyloid plaque deposits, neurofibrillary “tangles”
and impaired cognitive functioning. According to the researchers, the study demonstrates that Alzheimer's is a brain-specific
disorder, distinct from other types of diabetes, such as the inherited form, Type 1, and obesity-linked Type 2.
However, many experts are skeptical. Sam Gandy, M.D., Ph.D., Director of the Farber Institute for Neurosciences of Thomas
Jefferson University, is unconvinced of the research. “To date, the construct that Alzheimer’s is Type 3 diabetes remains
largely unsupported,” said Dr. Gandy.
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Jefferson Neurosurgeons First in Region to Use Innovative Stent to Open Clogged Arteries in the Brain, Prevent Strokes(Published 3-17-06) Neurosurgeons at Thomas Jefferson University Hospital in Philadelphia are the first in the region and
among the first in the nation to successfully use a new stent specifically designed to open potentially life-threatening clogged
arteries in the brain, preventing a stroke.
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Diagnosing a stroke(Published 3-13-06, Reading Eagle) If you received an email about diagnosing a stroke, you should be aware that the three-part
test proposed as a magic bullet could be seriously misleading. Doctors say a bystander can recognize a stroke by asking three
simple questions:
1. Ask the individual to smile.
2. Ask him or her to raise both arms.
3. Ask the person to speak a simple sentence (Coherently) (e.g., It is sunny out today). If he or she has trouble with any
of these tasks, call 9-1-1 immediately and describe the symptoms to the dispatcher.
Dr. Kiwon Lee, director of the Neurointensive Care Unit and Clinical Assistant Professor of Neurology and Neurosurgery at
Thomas Jefferson University Medical School, said the test may well identify some strokes, but it had serious shortcomings.
For example, he said he had just seen a patient with a stroke that would have passed "The Smile Test." The patient had what
is called a sensory stroke and his symptom was a "funny feeling" on one side of his body.
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The Nose Knows This New Surgery Technique(Published 3-9-06, KYW Newsradio) A local hospital is offering minimally-invasive surgery for removing brain tumors. The procedure
is similar to that of ancient Egyptian practices.
The breakthrough procedure at Thomas Jefferson University Hospital allows doctors to remove brain tumors through the nose
and nasal sinuses.
"In the past we used to use microscopes and big incisions to get into the sinuses and take out the tumor with a microscope.
Now we go straight into the sinus without making a lot of incisions and using the telescope we can take out the tumor,” says
Jefferson otolaryngologist-head and neck surgeon Dr. Marc Rosen. He says the method to approach the brain through the nose
has been around for a long time.
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Warning About Using Narcotics to Treat Migraines(Published 3-7-06, ABC News World News Tonight) A recent survey of 30 managed care plans showed nearly 70 percent of prescriptions
written for patients with headaches are for narcotics.
Specialists are now sounding the alarm. Narcotics, they said, are an unproven and risky treatment for headaches and should
rarely be used.
Dr. Stephen Silberstein, director of the Jefferson Headache Center at Thomas Jefferson University Hospital in Philadelphia,
said long-term use of narcotics can actually magnify headache pain and could render other treatments ineffective.
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Jefferson Offers Minimally Invasive Surgery for Removing Brain and Skull Base TumorsBreakthrough procedure allows doctors to remove brain tumors through nose and nasal sinuses
(Published 3-3-06) A state of the art program has opened at Thomas Jefferson University Hospital offering a new alternative
for people with brain and skull base tumors. The Jefferson Center for Minimally Invasive Cranial Base Surgery and Endoscopic
Neurosurgery is a comprehensive center in the Philadelphia area where surgeons are able to remove skull-based tumors through
nose and nasal sinuses instead of the traditional, more invasive surgery which required opening up the brain and skull.
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New Hope for MS Patients?
(Published 3-1-06, ABC News.com) Tysabri, a medication that treats the symptoms of the autoimmune disease multiple sclerosis,
may offer new hope for patients, but it also carries small life-threatening risks, according to three new studies published
in this week's New England Journal of Medicine.
Still, the potential benefits of Tysabri need to be weighed against the potential risk of acquiring PML and other side effects
associated with the medication, experts said.
And there are additional risks associated with the medication, said Dr. Thomas Leist, director of the Comprehensive Multiple
Sclerosis Center at Thomas Jefferson University in Philadelphia.
"What nobody talks about is that there is a small but not insignificant risk of increased infections — this is concerning
in patients with advanced MS who are at increased risk of acquiring infections," he said.
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New center at Jeff(Published 2-27-06, Philadelphia Business Journal) Thomas Jefferson University Hospital has launched a new center that will
specialize in patients affected by movement disorders such as Parkinson's disease, Huntington's disease, dystonia, and Tourette's
syndrome.
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Shedding Light on a Fading Mind(Published 2-26-06, Philadelphia Inquirer) Autopsies are the only way to truly diagnose dementia, but that may not be true
much longer. Scientists are racing to figure out what's going on in patients' brains while they can still be treated.
Sam Gandy, director of Thomas Jefferson University Hospital's Farber Institute for Neurosciences, considers human brains crucial
for disease research based on animal models and for measuring the impact of drugs.
He started accepting brains for autopsy as soon as he came to Jefferson in 2001 and stepped up the effort last year. Scientists
also use archived brain tissue to test new theories.
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Jefferson recruits experts in Parkinson’s disease and Movement Disorders to head new center(Published 2-13-06) Thomas Jefferson University Hospital in Philadelphia has inaugurated a Movement Disorders Program directed
by recently recruited specialists, Tsao-Wei Liang, M.D., Assistant Professor of Neurology, Jefferson Medical College of Thomas
Jefferson University, and Daniel Erik Kremens, M.D., J.D., Clinical Assistant Professor of Neurology.
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Cloning Expert at Pitt Rebuked
(Published 2-11-2006, Philadelphia Inquirer) Gerald Schatten, a University of Pittsburgh scientist, did not help falsify a
fraudulent South Korean stem-cell paper, but he did cut corners, seek personal gain, and shirk his responsibility to verify
the research. Schatten had never even visited the Korean's lab nor was he a participant in Hwang's experiments, yet he “did
most of the writing” and revisions of the paper, an investigation reported.
“He was putting his name and his reputation on the line in the letter to Science,” said Lorraine Iacovitti, Ph.D., associate
director of the Farber Institute for Neurosciences of Thomas Jefferson University and professor of neurology at Jefferson
Medical College of Thomas Jefferson University. “Had everyone seen the paper, [the fakery] probably would have bubbled to
the surface much quicker - maybe even before publication.”
Schatten’s ability to publish, collaborate and get grants is likely to be affected, at least temporarily, Dr. Iacovitti said.
“He’s going to pay a price,” she added.
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Featured in the MediaObesity Linked to Alzheimers Disease Protein(Published 1-10-06, Reuters) A new study conducted at Thomas Jefferson University in Philadelphia shows that as body fat increases,
so do blood levels of a protein fragment linked to Alzheimer's disease.
"We found that obesity by itself, even in otherwise healthy middle-aged people, is associated with elevated levels of the
amyloid peptide that builds up and causes Alzheimer's," explained Sam Gandy, M.D., Ph.D., director of the Farber Institute
for Neurosciences of Thomas Jefferson University in Philadelphia and one of the study's central authors.
"Amyloid is normally made all throughout the body at various lengths," Gandy explained. "This particular form is believed
to be the form that initiates build-up of amyloid plaques in the brain."
Dr. Gandy and his colleagues investigated whether levels of the peptide, plasma amyloid-beta 42, were related to body mass
index (BMI) or fat mass in 18 healthy adults. A direct correlation between the levels of amyloid-beta 42 in the bloodstream
and the body mass index was found.
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Drug Slows Alzheimer's Progression(1-9-06) A drug approved to treat moderate to severe forms of Alzheimer's disease appears to slow progression of the illness
by nearly 50 percent for up to one year, a new study found. Although the drug is the only one approved for use by patients
with severe Alzheimer's, it is thought Namenda might benefit patients in the early stages of the disease as well.
"The good news is that the drug's benefit, albeit modest, lasts longer than previously documented," said Sam Gandy, M.D.,
Ph.D., director of the Farber Institute for Neurosciences of Thomas Jefferson University in Philadelphia.
"One wonders whether the drug might be showing some disease-modifying properties that were not seen with shorter-term uses,"
he added. "More basic and clinical work will need to be done before one can draw this conclusion, but more investigation is
warranted.”
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Sharon Undergoes All-Night Surgery(Published 1-5-06, 6ABC(Ch.6)) Prime Minister Ariel Sharon was in serious condition following seven hours of emergency surgery
to stop widespread bleeding in his brain caused by a life-threatening stroke, doctors said.
Jefferson Hospital's Chair of Neurosurgery Robert Rosenwaser, M.D., FACP, talks to 6ABC News about Sharon's surgery and his
prognosis.
You can watch Dr. Rossenwasser's interview in an online video by going to 6ABC's web site.
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Three Specialists from Jefferson’s Acute Stroke Center Are First to Receive Newly Created Certification in Vascular Neurology (Published 8-5-05) Three stroke specialists with the Acute Stroke Center at Thomas Jefferson University Hospital are among
the first neurologists in the nation to receive a newly created certification in vascular neurology or stroke.
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Big News About Migraines, Botox
(Published 6-24-05, NBC 10) The American Headache Society is meeting in Philadelphia. So all the big experts are here and
all the big news is coming out of here. And with good reason. About 28 million Americans get migraine headaches, and one in
every five women. Now doctors say if you get throbbing headaches that keep you from moving, even if the pain is on both sides
of your head, that is almost certainly a migraine.
What's new about migraines? They're not caused by the blood vessels in your head.
"The headache itself is like inflammation of the lining of the brain. Migraine is like hives of the brain," says Steven Silberstein,
M.D. director of the Jefferson Headache Center at Thomas Jefferson University Hospital.
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Schiavo autopsy: There was no hope(Published 6-16-05, Philadelphia Inquirer) What caused Teri Schiavo's brain damage remains a mystery, but Florida medical
authorities, who released the results of her brain autopsy yesterday, said the injury was "massive" and "irreversible," and
left her blind.
Brain experts, including two at Thomas Jefferson University, who read the autopsy praised its thoroughness and agreed that
it showed extensive damage from which there was no hope of recovery.
"This is horrendous, horrific and irreversible," said David Brock, M.D., neurologist at Thomas Jefferson University Hospital.
In addition to the blindness, the autopsy showed that Schiavo's hippocampus, the seat of memory in the brain, was profoundly
damaged, said Lawrence Kenyon, M.D., Ph.D., a neuropathologist at Thomas Jefferson University Hospital. "If you have damage
to your hippocampus, you cannot remember anything, so there is no way for you to learn or improve at all," he said.
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To Benefit MS Research, Family Strikes Chord with Annual Concert Fundraiser
(Published 5-19-05) Grateful for the care their loved one received at the Comprehensive Multiple Sclerosis Center at Philadelphia’s
Thomas Jefferson University Hospital, a Radnor, Pa. family orchestrates an annual fund-raiser concert at New York City’s
Carnegie Hall. This year’s "Music from the Heart" concert, is scheduled for
8 p.m. on June 3.
Carnegie Hall Concert Will Benefit Research at Jefferson’s Multiple Sclerosis Center
(Published 5-11-05) A Carnegie Hall concert to benefit multiple sclerosis (MS) research, featuring Philadelphia area school
choirs, will be held 8 p.m. on Friday, June 3, in New York City.
(Published 7-28-06) Taking advantage of a 12-year history of providing the most innovative treatment for patients with brain
tumors, physicians in three departments of the Kimmel Cancer Center at Thomas Jefferson University and Thomas Jefferson University
Hospital have joined together to expand the service. Featured in the Media
Top Docs 2006
(Published 7-05-06) Among the 2006 "Top Docs" profiled in Philadelphia Magazine are Barry Rovner, M.D., geriatric psychiatrist
and director of the Alzheimer’s Center at the Farber Institute for Neuroscience, Thomas Jefferson University, and neurologist
Rodney Bell, M.D., director of the Acute Stroke Center at Thomas Jefferson University Hospital.(Published 7-28-06) Taking
advantage of a 12-year history of providing the most innovative treatment for patients with brain tumors, physicians in three
departments of the Kimmel Cancer Center at Thomas Jefferson University and Thomas Jefferson University Hospital have joined
together to expand the service.
Featured in the Media
Published 7-28-06) Taking advantage of a 12-year history of providing the most innovative treatment for patients with brain
tumors, physicians in three departments of the Kimmel Cancer Center at Thomas Jefferson University and Thomas Jefferson University
Hospital have joined together to expand the service.
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