September 2005
Jefferson Study to Evaluate Impact of Procedure in Preventing Premature Birth
(Published 9-19-2005) Physicians in the Maternal-Fetal Medicine Program at Thomas Jefferson University Hospital are participating
in a nationwide study to learn if cerclage--a “stitch” placed at the base of a woman’s cervix to ensure that it is kept closed
during pregnancy--is beneficial in delaying or preventing preterm or premature birth in those women with a history of prior
premature birth.
Understanding IGF-1: Jefferson Researcher Sees Drug Potential in Targeting Protein
(Published 9-19-2005) According to Dr. Baserga, who is professor of microbiology and immunology at Jefferson Medical College
of Thomas Jefferson University in Philadelphia and acting director of Jefferson’s Kimmel Cancer Center, in the past few years,
scientists have learned that the IGF-1 receptor is also a key growth factor that regulates cell and body size.
Jefferson Scientists Design Method to Fight Artificial Implant Infections with Antibiotics
(Published 9-23-2005) Infections associated with inserting a medical device can be devastating, painful, and cause prolonged
disability, costing tens of thousands of dollars.
Now, researchers at Jefferson Medical College have found a way to create a permanent chemical bond between antibiotics and
titanium, a material used in orthopedic implants. The proof-of-principle study showed that an antibiotic can be connected
to the titanium surface in an active form, and can kill bacteria and prevent infection. The work is a critical first step
toward developing stable, bacteria-resistant implants to combat infection.