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Autopsy will reveal damage
(Published 3-30-05, The Philadelphia Inquirer)  Brain experts say an autopsy of Terri Schiavo, the Florida patient who has been in a persistent vegetative state for a number of years, will likely reveal that much of her brain is shrunken and scarred.
David Brock, M.D., Director of the Neurologic Intensive Care Unit at Thomas Jefferson University Hospital, looked at a 2002 scan of Schiavo posted on the Internet. "The scan shows 'catastrophic' injury to the cerebral cortex, the part of the brain that controls all higher functions," he said.
Dr. Brock said the scan is consistent with laminar necrosis, in which layers of the brain become disconnected and unable to communicate.
A Jefferson neuropathologist, Lawrence Kenyon, M.D., Ph.D. who is also assistant professor of Pathology at Jefferson Medical College of Thomas Jefferson University said an autopsy will show which parts of the brain are missing or damaged.  The process usually takes three to four weeks.
Department of Neurology
Department of Pathology

Media Coverage:
Philadelphia Inquirer


Treating Bipolar Disorder in Teens
(Published 3-30-2005) Your Morning on CN8/Comcast, 9-11 a.m.) Gail Edelsohn, M.D., director of child and adolescent psychiatry services, Thomas Jefferson University Hospital, discusses a new study she is conducting called the "Bipolar Disorder (BD) Center for Pennsylvanians."  The study's goal is to
investigate Bipolar Disorder among adolescents, ages 12 to 17, to determine what treatment approaches are most effective. Bipolar Disorder (BD) in teens is now on the rise. The trial is being funded by a $770,000 grant for the state Dept of Health and Jefferson in the only site studying BD in adolescents.
Department of Psychiatry and Human Behavior
Child Adolescent Psychiatry Outpatient Services

News Release: Jefferson’s New Bipolar Disorder Center is Studying Safe Treatments for Adolescents


Stormy Weather May Mean Agony For Migraine Sufferers
(Aired 3-24 -05, WCAU-TV Ch. 10)  Not many people enjoy stormy weather.  But those who suffer from migraines may have an additional reason to dislike stormy weather.
“I can see when the fronts are coming and I know that they might be a bad day for me,” said Sharon Kane, a migraine sufferer from Drexel Hill, Pa.
At the Jefferson Headache Center, doctors suggest keeping a record of when your migraines happen. “Find out what days you have the headache and then go and get the barometric pressure weather report, and you can see if the weather triggered your headache, said Stephen Silberstein, M.D., professor of Neurology, Jefferson Medical College of Thomas Jefferson University.
Department of Neurology
Headache Center
Jefferson Hospital for Neuroscience 

Media Coverage:
NBC 10
** Also picked up by NBC affiliates nationwide.


Stethoscope's practicality grows fainter
(Published 3-27-2005, Chicago Sun Times) A raft of studies has found an alarming decline in doctors' stethoscope skills. The most recent evidence comes from the University of Chicago, where a study of fourth-year medical students found that students using stethoscopes reported accurate findings only 33 percent of the time. A lead author of such studies, Sal Mangione, M,.D, of Jefferson Medical College, said doctors perform better when listening to the lung. Abnormal lung sounds are easier to detect, and there's more time between breaths than between heartbeats. Moreover, portable ultrasound devices don't work well on lungs. Nevertheless, Dr. Mangione says new technology eventually will replace stethoscopes. "We have better tools," he said.
Division of Critical Care, Pulmonary, Allergic, Immunologic Diseases
Department of Medicine

Media Coverage:
Chicago Sun Times


Dehydration death seen as peaceful
(Published 3-27-05, The Philadelphia Inquirer) The condition of Terri Schiavo, the Florida patient who has been in a persistent vegetative state for a number of years, was in the news after her feeding tube was removed.
Paul Marik, M.D., director of the Division of Pulmonary and Critical Care at Thomas Jefferson University Hospital, discussed the situation. Schiavo may react reflexively to pain, he said, since only the most primitive part of her brain, the brain stem, is working. The higher parts of her brain are incapable of perceiving that pain.
Pain is a conscious interpretation of what's happening. If you can't interact with the environment, if you're not awake and you're not conscious, you can't perceive pain, Dr. Marik said. It's a very painless and very compassionate way of dying.
Division of Critical Care, Pulmonary, Allergic, Immunologic Diseases

Media Coverage:
Philadelphia Inquirer
Macon.com
Ledger Enquirer
SanLoisObispo.com
TimesLeader.com
Duluth News Tribune
Bradenton Hearald
FortWayne.com
MyrthleBeachOnline.com
Sun Hearld
Tallahassee.com
Grand Forks Herald


Pennsylvania Department of Health Awards Jefferson $3.5 Million from Tobacco Settlement Funds to Establish a New Center of Excellence on Neurodegenerative Diseases
(Published 3-17-05, PR Newswire)  Sam Gandy, M.D., PH.D. is principal investigator of a four-year, $3.5-million grant from the Pennsylvania Department of Health to support a Center of Excellence on Neurodegenerative Diseases at the Farber Institute for Neurosciences at Thomas Jefferson University in Philadelphia.  The health research grant is awarded from Pennsylvania’s share of the national tobacco settlement.
The new Jefferson center, co-directed by Barry Rovner, M.D., and Laura Gitlin, PH.D., will work in collaboration with the Philadelphia Corporation for Aging, in order to conduct several research projects, each focusing on a different aspect of the Alzheimer’s disease equation.
“The unique aspect of this project is the focus on developing a convenient diagnostic test that many caregivers and case workers can administer, and on training caregivers in non-drug related strategies that can help keep patients at home longer prior to nursing home placement,” says Dr. Gandy.
Farber Institute for Neurosciences

Media Coverage:
PR Newswire
WIVB
Black Enterprise
Volunteertv.com
WECT
Dcbank.com
KPHO
KPTV
Nurse Week


For Jeff med students, the alternative is a requirement
(Published 3-11 to 3-17-05, Philadelphia Business Journal)  Medical students at Thomas Jefferson University receive extensive exposure to complementary and alternative medicine before graduating. Steven Rosenzweig, M.D., medical director of the Jefferson-Myrna Brind Center for Integrative Medicine at Thomas Jefferson University Hospital and associate professor of Emergency Medicine at Jefferson Medical College of Thomas Jefferson University, discusses the current medical school curriculum and how it has been revamped over the years. "In 2005, we are teaching integrative medicine. We are giving students a coherent framework in which there is a good rationale for integrating complementary and alternative therapy within a mainstream setting," he says.
Jefferson-Myrna Brind Center for Integrative Medicine at Thomas Jefferson University Hospital


More women turn to cesarean section
(Published 3-20-05, Philadelphia Inquirer) Louis Weinstein, director of Obstetrics and Gynecology, Jefferson Medical College of Thomas Jefferson University, speaks about the trend against vaginal births after a previous cesarean. "It is not difficult to direct a patient" when discussing methods of delivering a baby, he says.

Media Coverage:
Philadelphia Inquirer


Cancer Society's "Daffodil Day" Overflows into Jefferson Hospital
(Aired 3-18-05, KYW Newsradio 1060 AM)  Thomas Jefferson University Hospital employees participated in the local American Cancer Society's "Daffodil Day" that brought much-needed smiles to cancer patients.  Flowers were donated to brighten up the rooms of cancer patients who are in the hospital as well as to patients who are receiving treatment on an outpatient basis. "We were overwhelmed by the response of Jefferson employees.  Actually, we were really overwhelmed, because we didn't expect as many (donations) as we got," said Ann Delengowski, oncology nurse at Jefferson University Hospital. "The daffodil is for hope, and anyone who comes to the cancer center has the hope of being cured," said outpatient Carol Conte of Blackwood, N.J.
Department of Radiation Oncology

Media Coverage:
KYW 1060


Morley's descent began at tender age
(Published 3-20-2005, Philadelphia Inquirer) Gail Edelsohn, M.D., director of child and adolescent psychiatry services at Thomas Jefferson University Hospital, discusses case of 15-year-old Justine Morley, who led a young boy to his death. Dr. Edelsohn wondered what role drugs and group dynamics played in the murder and the girl's behavior. "People who otherwise would not do horrible things will do them in drug-related situations," she said.
Department of Psychiatry and Human Behavior
Child & Adolescent Psychiatry Outpatient Services

Media Coverage:
Philadelphia Inquirer


Do MDs or MBAs Make Better Leaders?
(Published March, 2005, HealthLeaders)  In the cover story of the March issue of HealthLeaders, the question of whether physicians or MBAs make better CEOs of health-care organizations is examined.  David Nash, M.D., MBA, chair of the Department of Health Policy at Jefferson Medical College of Thomas Jefferson University, is highlighted for his role as a leading advocate for combining medical and business education.

Media Coverage:
HealthLeaders.com>


Rendell Administration Announces Health Research Grants From Tobacco Settlement Funds
(Published 03-16-2005, Yahoo! Finance)  On behalf of Pennsylvania Governor Edward G. Rendell, Health Secretary Dr. Calvin Johnson announced that five health research grants totaling $20 million will be awarded from Pennsylvania's share of the national tobacco settlement.  These grants will develop Centers of Excellence to reduce disparities in neurodegenerative diseases and tobacco use.  Thomas Jefferson University, in collaboration with the Philadelphia Corporation of Aging, will receive $3.5 million to test biological markers and a community-based screening tool to identify dementia in a racially and economically diverse community.  The project will also test the efficacy of a home-based caregiver kills-training intervention to delay nursing home placement and improve the quality of life for caregivers. "This year's grants reaffirm the Rendell Administration's commitment to identifying and funding projects that will have a positive impact on our residents and their health," says Secretary Johnson.
Farber Institute for Neurosciences

Media Coverage:
Yahoo Finance
KPHO
PR Newswire
Volunteertv.com
WIVB
Forbes
Black Enterprise
PR Newswire
WECT
WNBS 10 TV>


Advanced Radiation for Hard-to-Treat Brain Tumors
(Aired 03-11-2005, Ch. 6)  Walter J. Curran, M.D., professor and chair of Radiation Oncology at Jefferson Medical College of Thomas Jefferson University and clinical director of the Kimmel Cancer Center at Jefferson and David Andrews, M.D., professor of neurosurgery at Jefferson Medical College of Thomas Jefferson University and director, Division of Neuro-oncologic Neurosurgery and Stereotactic Radiosurgery, Thomas Jefferson University Hospital, discuss Shaped Beam Surgery, a new type of targeted radiation for hard-to-treat brain tumors. "We have the ability to define a target, and give a dose to that target with relatively little dose to the surrounding structures," says Dr. Curran. "We have had a marvelous experience, treating patients with tumors encasing the optic nerve. Patients are going blind, and after this treatment, they may regain vision during the treatment, or their vision is restored in the first three months," adds Dr. Andrews.
Department of Neurology
Department of Neurosurgery
Department of Radiation Oncology

Media Coverage:
ABC 6


The Most Depressed City in U.S.?
(Published 3-17-05, 9:45 a.m., Your Morning on CN8,Comcast,) Psychiatrist Troy L. Thompson, II, M.D. of Thomas Jefferson University comments on a new Men's Health magazine study, indicating that Philadelphia is the most depressed city in the nation. Dr. Thompson says the survey may be askew. He notes there is a public stigma regarding depression and some doctors in other cities may be reluctant to diagnose and treat the illness, and patients there may be reluctant to accept treatment or medications for depression.

But in Philadelphia, doctors may be more willing to be responsible and diagnose and treat patients for, and educate patients about, depression, thus accounting for more reported cases of depression here.


Lack of Insulin Linked to Alzheimer's
(Published 03-07-2005, HealthDay)  Two discoveries about insulin may shed new light on how Alzheimer's disease ravages the brain, and might one day lead to new treatments.  One discovery, made by a team at Brown University, is that insulin is produced in the brain; the second is that Alzheimer's patients have impaired insulin production in their brains.  Samuel Gandy, M.D., director of the Farber Institute for Neurosciences at Thomas Jefferson University, comments on these recent findings.  He says that while the suggestion of insulin's role in Alzheimer's is interesting, there are problems with the Brown study that make the link less than convincing. Part of the problem is using brain tissue of deceased Alzheimer's patients, because that makes it impossible to tell at what point changes in the tissues occurred. "There are lots of changes that are very late and very far down the pathogenetic stream, so it's hard to tell what's the chicken and what's the egg," he notes.

Media Coverage:
Health Day
Red Nova
Dcbank.com


The Kindest Cut?
(Published 03-08-2005, The Washington Post)  Stephen Silberstein, M.D., director of the Headache Center at Thomas Jefferson University, comments on the results of a study done by Bahman Guyuron, a plastic surgeon, which used plastic surgery to treat migraines.  One concern, he says, is Guyuron's reliance on Botox, which has been shown to have a high placebo response.  About 40 percent of patients in some studies did as well after being injected with a dummy liquid as with Botox, one reason the Food and Drug Administration has not approved the wrinkle smoother as a migraine treatment.
Department of Neurology
Headache Center

Media Coverage:
Washington Post


Non-Invasive Device Shown To Help Heart Failure Patients
(Published 03-08-2005, Excite.com)  Heart failure patients who underwent a non-invasive therapy designed to improved blood flow, called external counterpulsation therapy (EECP), were able to exercise longer after six months of treatment. "The results showed that six months after treatment with EECP therapy, significantly more patients increased their exercise time compared with those receiving optimal drug therapy alone," says Arthur Feldman, M.D., professor and chair, Department of Medicine, Jefferson Medical College of Thomas Jefferson University, who was the principal investigator. "That improvement, together with improvements seen in symptom status and quality of life, support the use of EECP therapy as an adjunctive treatment for chronic stable heart failure patients," he adds.
HeartCARE at Jefferson
Division of Cardiology

Media Coverage:
My Way - Finance
Excite Money
IWon.com - Money
Dcbank.com
Stockhouse.com
Pharmacy Times.com
Yahoo - Finance


Clinton to Undergo New Surgery
(Aired 03-08-2005, NBC 10)  Former President Bill Clinton will undergo surgery on Thursday to remove scar tissue and fluid from his chest cavity, a complication from his open-heart surgery.  Cardiologist Howard Weitz, M.D., Thomas Jefferson University Hospital, gives insight about the condition. "It's the typical way these patients present.  After open heart surgery, sometimes fluid compresses the lung and prevents the lung from expanding fully. The patient experiences a shortness of breath and realizes that something is wrong," he says.
HeartCARE at Jefferson
Division of Cardiology

Media Coverage
NBC 10


New Drive Brings Awareness To DVT
(Aired 03-04-2005, NBC 10)   Geno Merli, M.D., Director, Division of Internal Medicine, Thomas Jefferson University, discusses the symptoms of Deep Vein Thrombosis (DVT) which can lead to dangerous blood clots in a person's lungs. "The most common symptoms of deep vein thrombosis are leg swelling, pain in the leg or increased warmth of the leg.  And the most common symptom of pulmonary embolism is the sudden onset of shortness of breath," he says. A recent study finds that 74 percent of Americans have never heard of deep vein thrombosis although more than two million people suffer from the condition each year.  A new Public Service Announcement and website have been created to raise awareness, and Congress has passed a bill proclaiming March DVT Awareness Month.
Division of Internal Medicine

Media Coverage:
NBC 10
MSNBC
NBC 11


AIDS Killer
(Aired 03-03-2005, ABC 6)  Roger J. Pomerantz, M.D., director of the division of Infectious Disease and Environmental Medicine, Jefferson Medical College of Thomas Jefferson University, and his team have found a way to eradicate more of the HIV virus in patients.  They have found a protein called IL-7 that can "trick" HIV out of its hiding spots in cells. "I think it's important to realize the old saying that close only counts in hand grenades and horseshoes.  It doesn't count in HIV therapy.  We can't get most of it.  We have to get all of it to win," he says.
Division of Infectious Disease and Environmental Medicine

Media Coverage:
ABC 6
ScienCentral
http://www.wnep.com/Global/story.asp?S=3021584


Raising Awareness of Deep Vein Thrombosis
(Published 03-03-2005, Yahoo! Finance)  Geno Merli, M.D., Director, Division of Internal Medicine, Thomas Jefferson University, discusses a resolution in the United States Senate sponsored by Senators Arlen Specter (R-PA) and Byron Dorgon (D-ND) to raise public awareness of deep-vein thrombosis.
"It will take all our collective efforts to continue to raise the level of awareness about this common yet preventable condition.  The resolution passed today is a broad step towards our goal," he says.
Division of Internal Medicine

Media Coverage:
Yahoo - Finance


Bipolar Disorder in Teens
(Aired 3-6-2004, KYWNewsradio1060AM) Dr. Gail Edelsohn, director of child and adolescent psychiatry services, Thomas Jefferson University Hospital, discusses a new study she is conducting called the "Bipolar Disorder Center for Pennsylvanians."  The study's goal is to investigate Bipolar Disorder among adolescents, ages 12 to 17, to determine what treatment approaches are most effective.  Bipolar Disorder in teens is now on the rise.
Department of Psychiatry and Human Behavior
Child Adolescent Psychiatry Outpatient Services

Media Coverage: KYW 1060

In the Womb
(Aired 3-4-2005, ABC's Good Morning America) Ultrasound Specialist Dr. Anna Lev-Toaff of Thomas Jefferson University will discuss the latest technology and her research in 3D and 4D ultrasound fetal imaging.
Department of Radiology
Department of Obstetrics and Gynecology