Goldberg J, Burd I, Price FV, Worthington-Kirsch R. Leiomyosarcoma in a pre-menopausal patient following uterine artery embolization.
Am J Obstet Gynecol 2004;191:1733-5.
The first reported uterine sarcoma (cancerous fibroid) in a premenopausal woman following UAE. Given the difficulty in diagnosing
leiomyosarcoma and the increasing popularity of uterine artery embolization, in lieu of myomectomy or hysterectomy, which
provide a pathologic specimen, an increasing number of leiomyosarcomas will be unavoidably delayed in diagnosis. As other
gynecologic problems, including cancer, may co-exist or develop later in the presence of uterine fibroids, a lack of clinical
response to a technically successful embolization should alert care-providers that further evaluation and/or therapy is needed.
Mude-Nochumson H, Goldberg J. Fertility-sparing treatment options for women with symptomatic fibroids. Female Patient 2003;28:21-6.
Fertility-sparing Treatment Options for Women With Symptomatic Fibroids
63K pdf file
Goldberg J, Pereira L, Diamond J, Berghella V, Daraï E, Seinera P, Seracchioli R. Pregnancy outcomes following treatment
for fibroids: uterine artery embolization versus laparoscopic myomectomy. Am J Obstet Gynecol 2004;191:18-21.
The first published study comparing pregnancy outcomes in patients with fibroids previously treated with UFE and myomectomy.
Pregnancies following UAE had higher rates of preterm delivery (OR 6.2, 95% CI 1.4, 27.7) and malpresentation (OR 4.3, 95%
CI 1.0, 20.5) than pregnancies following LM. The risks of postpartum hemorrhage (OR 6.3, 95% CI 0.6, 71.8) and spontaneous
abortion (OR 1.7, 95% CI 0.8, 3.9) following UAE were similarly higher than the risks following LM, however, these differences
were not statistically significant.
Pregnancy outcomes following treatment for fibromyomata: uterine artery embolization versus laparoscopic myomectomy
234K ppt file
Goldberg J, Pereira L, Mude-Nochumson H. Uterine artery embolization for symptomatic fibroids. OBG Management, April 2003:69-79.
Uterine artery embolization for symptomatic fibroids
229K pdf file
Muffly T, Goldberg J, Goldberg B. Leiomyoma degeneration during pregnancy masquerading as uterine rupture. Female Patient
2003;28:53-4.
Fibroid degeneration during the second trimester of pregnancy in a patient who had previously undergone myomectomy which clinically
and radiologically presented as a uterine rupture.
Gopal M, Goldberg J, Klein T, Fossum G. Embolization of uterine arteriovenous malformation followed by a twin pregnancy. Obstet
Gynecol 2003;102:696-8.
A large vascular malformation within the uterine wall was successfully embolized. Following this the patient conceived and
had an uneventful twin pregnancy.
Yeagley T, Goldberg J, Klein T, Bonn J. Labial necrosis after uterine artery embolization for leiomyomas. Obstet Gynecol 2002;100:881.
The first case report of non-target embolization of the labia minora, which was successfully managed conservatively with pain
medications.
Goldberg J, Berghella V, Pereira L. Pregnancy after uterine artery embolization. Obstet Gynecol 2002;100:869-72.
The first comprehensive analysis of pregnancy outcomes following uterine artery embolization (UAE) for uterine fibroids. Higher
rates of complications, including preterm delivery (28%), malpresentation/breech (17%), cesarean delivery (58%), and postpartum
hemorrhage (13%), followed UAE than in the general population. Following publication of this series, desire for future fertility
is now considered a relative contra-indication.
Sultana CJ, Goldberg J, Aizenman L, Chon JK. Vesicouterine fistula after uterine artery embolization: A case report. Am J
Obstet Gynecol 2002;187:1726-7.
The first case report of a vesico-uterine fistula and extrusion of a degenerating fibroid into the bladder after UAE, necessitating
hysterectomy and partial cystectomy for repair.
Goldberg J. Pregnancy after uterine artery embolization for leiomyomata: The Ontario Multicenter Trial. Obstet Gynecol 2005;106:195-6.
Commentary on this multicenter study
Goldberg J. Uterine artery embolization for adenomyosis: looking at the glass half full. Radiology 2005;236:1111-2.
Commentary. Adenomyosis is a common disease affecting the uterus, which presents with symptoms similar to fibroid disease.
Treatment options are limited for symptomatic women. The most treatment with the highest success rate is hysterectomy. In
the eighteen women with adenomyosis treated with uterine artery embolization, there was improvement in menorrhagia in 94%
of subjects at 6 months. After two years, however, only 56% still had improvement in of menorrhagia. Uterine artery embolization
may be appropriate in the subsets of patients with symptomatic adenomyosis desiring future fertility, who have increased surgical
risk due to adhesive disease or those absolutely desiring uterine preservation.
Goldberg J, McCrosson S, Kaulback KR. Fibroid degeneration following microwave endometrial ablation. Obstet Gynecol 2005;106:1176-8.
First case report of delayed fibroid degeneration occurring in a series of patients following microwave endometrial ablation
(MEA) for abnormal uterine bleeding.
Goldberg J, Boyle K, Choi M, Panchal N. Bowel obstruction following uterine fibroid embolization. Am J Obstet Gynecol 2005;193:892-3.
First case report of an intra-abdominal adhesion caused by UFE leading to bowel entrapment and obstruction. The obstruction
was quickly recognized and relieved with laparotomy and lysis of the adhesion, with avoidance of bowel resection.
Goldberg J. Uterine fibroid embolization : A new treatment for uterine fibroids. Female Patient 2006;31:45-50.
A comprehensive review article on UFE.
Goldberg J, Mella MT. Uterine fibroid embolization complicated by non-target labial embolization. Female Patient 2006;31:26-7.
The second case report of this rare complication of UFE, which was managed conservatively. Although the necrotic labial area
cosmetically resolved, the patient has a persistent change in labial sensitivity.
Goldberg J, Pereira L. Pregnancy outcomes following uterine fibroid embolization and myomectomy. Current Opin Ob Gyn 2006;18:402-6.
Goldberg J, Cothran S, Bonn J. Pre-myomectomy uterine fibroid embolization for a massively enlarged fibroid uterus. Female
Patient 2006;31:1-3.
Goldberg J, Bussard A, McNeil J, Diamond J. Cost and reimbursement for three fibroid treatments: Abdominal hysterectomy, abdominal
myomectomy, and uterine fibroid embolization. CVIR 2007; 30:54-8.
Goldberg J. Current thinking on the role of interventional radiology in women’s health . Expert Opin Gyn Obstet 2007;2:621-9.
Expert Review IR in Woman's Health
Myometrial air infiltration following postpartum UAE: Imaging findings
Presented at 36th Global Congress of Minimally Invasive Gynecology, Washingtin, DC, 2007.
187K pdf file
Perceptions of patients desiring fertility of fibroid treatments .
Presented at the ACOG Annual Clinical Meeting in New Orleans, May 2008
1.21 MB ppt file
Perceptions of patients NOT desiring fertility of fibroid treatments.
Presented at the ACOG Annual Clinical Meeting in New Orleans, May 2008
1.84 MB ppt file

Jefferson Medical College students, Michelle Hellman and Dominic Femiano, involved in fibroid research.

Jenna Angelo and Michelle Hellman present their fibroid study at the 2008 ACOG Annual Clinical Meeting in New Orleans.
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 Dr. Jay Goldberg and Dr. Sean McConnell presenting at the 36th Global Congress of Minimally Invasive Gynecology, Washington,
DC, 2007.
 Jefferson faculty and alumni at the 36th Global Congress of Minimally Invasive Gynecology, Washington, DC, 2007.
 Jefferson's Jay Goldberg, Jesica Bromberg, Jolene Seibel-Seamon, and Anne Bussard present their research at the 2nd NIH International
Congress of Advances in Uterine Leiomyoma Research in Bethesda, February 2005
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 Anne Bussard and Jay Goldberg present their research at 2nd NIH International Congress of Advances in Uterine Leiomyoma Research
on costs and reimbursements for 3 fibroid treatments (myomectomy, hysterectomy, and uterine fibroid embolization).
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 Jolene Seibel-Seamon presents her research at 2nd NIH International Congress of Advances in Uterine Leiomyoma Research which
evaluated the FDA's MAUDE database and the scientific literature with regard to complications following uterine fibroid embolization
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 Jay Goldberg and Jesica V. Bromberg present their research at the 2nd NIH International Congress of Advances in Uterine Leiomyoma
Research on the effect of uterine fibroids on pregnancy outcomes.
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 Drs. Leo Pereira, Jorge Tolosa, and Jay Goldberg at FIGO's International Congress in Chile.
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 Dr. Leo Pereira and Jay Goldberg present research at FIGO meeting in Chile.
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Drs. Leo Pereira, Jay Goldberg, and Vincenzo Berghella
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