The following clinical trials are currently open at Jefferson.
Learn about participating in clinical trials

 

Open Clinical Trials and Research Studies as of October 2009

Jefferson Pancreas Tumor Registry A research study that consists of completing patient, family and non-family questionnaires to collect and analyze data about family history, demographic variables and environmental/occupational risk factors of current pancreatic cancer patients.

Fatigue, Physical Functioning, and Quality of Life in Patients with Pancreatic and Periampullary Cancers Following Surgery, Chemotherapy and/or Radiation Therapy The purpose of this pilot study is to determine the effects of a walking program on fatigue, physical functioning and quality of life (QOL) in post-operative patients with pancreatic cancer (PC) and periampullary cancers (bile duct, ampulla, duodenum) who  have had surgery alone or are undergoing adjuvant therapy with chemotherapy (CT) and/or radiation therapy (RT).

A Randomized Trial of Two Surgical Techniques for Pancreatic Remnant Closure in Patients Undergoing a Distal Pancreatectomy The purpose of this trial is to determine whether a standard closure or closure with fibrin glue and patch will improve the pancreatic fistula rate after distal pancreatectomy.

Collection, Banking and Evaluation of Tissues, Blood, Pancreatic Juice and Bile Samples are collected from patients with pancreatic and related carcinomas while undergoing surgical resection.

A Randomized Controlled Trial of Intraoperative Celiac Plexus Neurolysis for Patients with Operable (Resectable and Unresectable) Pancreatic and Periampullary Cancer (Phase III) A study to determine if the addition of an intraoperative alcohol nerve block in patients undergoing surgical intervention for pancreatic cancer will result in a decrease in cancer associated pain.

A Multinational, Randomized, Double-Blind Study, Comparing the Efficacy of Aflibercept Once Every 2 Weeks Versus Placebo in Patients Treated With Gemcitabine for Metastatic Pancreatic Cancer Primary Objective: To demonstrate improvement in overall survival (OS) with aflibercept by comparison to placebo in patients treated with gemcitabine for metastatic pancreatic cancer.

Vaccine Study for Surgically Resected Pancreatic Cancer (Phase II) Primary Objective: To assess the response for subjects with pancreatic cancer that have undergone surgical resection and treatment with a vaccine given with chemotherapy and chemoradiation.