Thomas Jefferson University Hospital
 
DEPARTMENT OF UROLOGY

Diseases and Conditions

Polycystic Kidney Disease

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Polycystic kidney disease (PKD) is a disorder characterized by the growth of numerous cysts filled with fluid in the kidneys. PKD cysts can reduce kidney function, leading to kidney failure. PKD can also cause cysts in the liver and problems in other organs, such as the heart and blood vessels in the brain. There are two primary inherited forms of PKD (autosomal dominant PKD and autosomal recessive PKD) and one non-inherited form (acquired cystic kidney disease).

PKD is the fourth leading cause of kidney failure and affects approximately 600,000 people in the United States. According to the National Kidney Foundation, about 50 percent of people with the autosomal dominant form of PKD progress to kidney failure, or end-stage renal disease (ESRD), by age 60. About 60 percent will have kidney failure by age 70.

Getting help at Jefferson
Although there is no cure for PKD, Jefferson physicians can help to alleviate the pain associated with this condition. Working closely with our team of nephrologists, Jefferson urologists provide surgical treatments, including minimally invasive laparoscopic procedures, to help shrink cysts and relieve pain.

Additional information about polycystic kidney disease